Serrapeptase: What is it and its importance for inflammation!

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serrapeptaseIn recent years, enzyme serrapeptase has gained popularity thanks to its unique properties and efficacy. However, many wonder where it comes from and how it works.

Serrapeptase: What is it?

It is a proteolytic enzyme, that is, it breaks down proteins into smaller components, the amino acids. It is isolated from bacteria found in silkworms’ saliva. It is this that helps them break their cocoon, and get out.

Serrapeptase: Properties


The various other proteolytic enzymes present were found to have anti-inflammatory properties in the United States in the 1950s. Japanese scientists discovered serrapeptase in the late 1960s, when they first isolated serrapeptase from silkworms and studied it. Now, many researchers in Europe agree with them, proposing serrapeptase as the most effective proteolytic enzyme for reducing inflammation. (1)

In particular, it breaks down fibrin and fibrinogen, and reduces inflammation and edema. Often, inflammations occur in the body after an injury, surgery, dental surgery or due to a disease, such as sinusitis, uterine adhesions, etc.

There are several studies in the field of dentistry that report that serrapeptase has helped reduce inflammation after removing fronimite, reducing pain and muscle spasms, as well as swelling in the face. However, its use in abscess is contraindicated as it can cause infection.

Another study on the effect of serrapeptase on postoperative swelling and ankle pain showed that in the serrapeptase-treated group, swelling decreased by 50% on the third postoperative day, whereas in the control group (without ice treatment and treatment) no swelling occurred. reduction. As a result, serrapeptase appears to be a good option for post-operative reduction of swelling compared to conventional precautionary measures (2).


Very often, serrapeptase is used for better vascular health. It seems to be able to remove dead cells and break down the plaques that form, helping to improve atherosclerosis!

Respiratory problems

A research study in Japan investigated the effect of serrapeptase on patients with chronic airway diseases. After 4 weeks of intake, phlegm, viscosity, and neutrophil counts were significantly reduced. In addition, coughing and expectoration decreased. The researchers concluded that serrapeptase may have a beneficial effect on mucus clearance, reducing neutrophil counts and altering the viscosity of phlegm in patients with chronic airway diseases. (2)

Serrapeptase: Instructions for use

The usual dose is 10-60mg of serapeptase. 10mg of serapeptase is equivalent to 20,000 enzyme units. (3) We will often see it in formulations at higher concentrations, as it is believed that a percentage is not absorbed. It is very important to state in the supplement that it is a enteric-soluble form, that is, it dissolves when it reaches the intestine, otherwise it is very likely to be destroyed by stomach acids.

It is important to take it on an empty stomach or at least 2 hours before a meal.

Serrapeptase: Side effects

Some of the possible side effects that may occur from taking it are nausea, anorexia, stomachache, cough, skin reaction or even muscle pain.

Serrapeptase: Contraindications

As there is evidence that serrapeptase may contribute to the breakdown of blood clots, it is recommended not to take contemporaneously with anticoagulants or dietary supplements such as garlic, fish oil (omega fatty acids), and turmeric, as the risk of hemorrhage may increase.

Find at a great variety in supplements with serrapeptase!


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